ProMotion Rehab and Sports Medicine - Florence
★★★★★ (358 reviews)610 W Palmetto St, Florence, SC 29501
(843) 407-0377
Website: physiosc.com
Hours: Mon: 8 AM–6 PM | Tue: 8 AM–6 PM | Wed: 8 AM–6 PM | Thu: 8 AM–6 PM | Fri: 8 AM–12 PM | Sat: Closed | Sun: Closed
Profection Physical Therapy
★★★★★ (291 reviews)2811 W Palmetto St Suite D, Florence, SC 29501
(843) 407-7010
Website: www.profectionpt.com
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–6 PM | Wed: 8 AM–5 PM | Thu: 8 AM–6 PM | Fri: 8 AM–1 PM | Sat: Closed | Sun: Closed
Crossroads Treatment Center of Florence, SC
★★★★☆ (119 reviews)1341 N Cashua Dr, Florence, SC 29501
(877) 848-9810
Website: www.crossroadstreatmentcenters.com/center/crossroads-of-florence-sc
Hours: Mon: 5–11 AM | Tue: 5–11 AM | Wed: 5–11 AM | Thu: 5–11 AM | Fri: 5–11 AM | Sat: Closed | Sun: Closed
Potter House Recovery
★★★★★ (92 reviews)308 S Coit St, Florence, SC 29501
(843) 615-5869
Website: www.potterhouserecovery.com
Hours: Mon: 8 AM–7 PM | Tue: 8 AM–7 PM | Wed: 8 AM–7 PM | Thu: 8 AM–7 PM | Fri: 8 AM–7 PM | Sat: 8 AM–7 PM | Sun: 10 AM–5 PM
The Palms at Florence
★★★★½ (101 reviews)4438 Pamplico Hwy, Florence, SC 29505
(843) 669-3502
Website: www.thepalmsatflorence.com
Hours: Mon-Sun: Open 24 hours
Encompass Health Rehabilitation Hospital of Florence
★★★★☆ (109 reviews)900 E Cheves St, Florence, SC 29506
(843) 679-9000
Website: www.encompasshealth.com/locations/florence-rehab
Hours: Mon-Sun: Open 24 hours
XGen Cryo Spa & Wellness Center
★★★★★ (84 reviews)1360 Celebration Blvd Suite C, Florence, SC 29501
(843) 731-9002
Website: xgencryo.com
Hours: Mon: 10 AM–7 PM | Tue: 10 AM–7 PM | Wed: 10 AM–7 PM | Thu: 10 AM–7 PM | Fri: 10 AM–4 PM | Sat: 10 AM–4 PM | Sun: Closed
The Owl's Nest Alcohol & Drug Addiction Treatment Center Florence SC
★★★★☆ (80 reviews)2528 W Palmetto St, Florence, SC 29501
(843) 919-4097
Website: owlsnestrecovery.com
Hours: Mon-Sun: Open 24 hours
Florence Neurosurgery & Spine at McLeod Health
★★★½☆ (84 reviews)1204 E Cheves St, Florence, SC 29506
(843) 673-0122
Website: florenceneurosurgery.com
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–1 PM | Sat: Closed | Sun: Closed
Health 1st
★★★★★ (59 reviews)311 W Palmetto St, Florence, SC 29501
(843) 662-2811
Hours: Mon: 8:30 AM–4 PM | Tue: 8:30 AM–4 PM | Wed: 8:30 AM–4 PM | Thu: 8:30 AM–4 PM | Fri: 8:30 AM–12 PM | Sat: Closed | Sun: Closed
Novant Health Physical Therapy – Florence (Formerly Progressive Physical Therapy)
★★★★½ (31 reviews)2200 S Irby St, Florence, SC 29505
(843) 669-0421
Website: novanthealthphysicaltherapy.org/Florence
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed
The Florence Presbyterian Community
★★★½☆ (37 reviews)2350 W Lucas St, Florence, SC 29501
(843) 206-0598
Website: www.prescommunities.org/senior-living/sc/florence/florence-presbyterian-community
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–5 PM | Sat: Closed | Sun: Closed
CORA Physical Therapy Florence
★★★★★ (26 reviews)2724 W Palmetto St # 2, Florence, SC 29501
(843) 292-1900
Website: www.coraphysicaltherapy.com/location/florence-south-carolina
Hours: Mon: Closed | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed
Florence Treatment Specialists
★★★★½ (27 reviews)1591 S Irby St, Florence, SC 29505
(843) 206-0845
Website: florencetreatmentspecialists.com
Hours: Mon: 5–11 AM | Tue: 5–11 AM | Wed: 5–11 AM | Thu: 5–11 AM | Fri: 5–11 AM | Sat: Closed | Sun: Closed
Vocational Rehabilitation Palmetto Center
★★★★½ (25 reviews)1709 Stokes Rd, Florence, SC 29501
(843) 662-9378
Website: www.scvrd.net
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–5 PM | Sat: Closed | Sun: Closed
Heritage Post Acute
★★★½☆ (32 reviews)515 Warley St, Florence, SC 29501
(843) 662-4573
Website: heritagepostacute.com
Hours: Mon-Sun: Open 24 hours
Faith Healthcare Center
★★★½☆ (27 reviews)617 W Marion St, Florence, SC 29501
(843) 669-9958
Website: www.faithhealthcentersnf.com
Hours: Mon-Sun: 8:30 AM–5:30 PM
Pee Dee Mental Health Center
★★☆☆☆ (33 reviews)125 E Cheves St, Florence, SC 29506
(843) 317-4073
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–5 PM | Sat: Closed | Sun: Closed
Palmetto Infusion - Florence, SC
★★★★★ (13 reviews)217 Dozier Blvd # 101, Florence, SC 29501
(800) 809-1265
Website: www.palmettoinfusion.com
Circle Park Behavioral Health Services
★★★½☆ (16 reviews)238 S Coit St, Florence, SC 29501
(843) 665-9349
Website: www.circlepark.com
Hours: Mon: Closed | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed
Promises Recovery
★★★★½ (11 reviews)521 S Coit St, Florence, SC 29501
(843) 536-6155
Website: www.promisesrecovery.org
Hours: Mon-Sun: Open 24 hours
MUSC Health Outpatient Rehabilitation Center
★★★★½ (11 reviews)1925 Hoffmeyer Rd 1st Floor, Florence, SC 29501
(843) 661-4360
Website: www.getcare.muschealth.org/locations/sc/florence/musc-health-outpatient-rehabilitation-centerdep-fac292
Hours: Mon: Closed | Tue: 7:15 AM–5:45 PM | Wed: 7:15 AM–5:45 PM | Thu: 7:15 AM–5:45 PM | Fri: 7:15 AM–5 PM | Sat: Closed | Sun: Closed
Vocational Rehabilitation Florence
★★★★½ (11 reviews)1947 W Darlington St, Florence, SC 29501
(843) 662-8114
Website: www.scvrd.net
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–5 PM | Sat: Closed | Sun: Closed
McLeod Outpatient Rehabilitation
★★★★☆ (11 reviews)2439 Willwood Dr, Florence, SC 29501
(843) 777-2043
Website: www.mcleodhealth.org/services/care/rehabilitation-overview/physical-therapy
Hours: Mon-Sun: Open 24 hours
Miracle Way Rehab Center
★★★★★ (7 reviews)704 W Evans St, Florence, SC 29501
(843) 713-1677
Hours: Mon: 8 AM–7 PM | Tue: 8 AM–7 PM | Wed: 8 AM–7 PM | Thu: 8 AM–7 PM | Fri: 8 AM–7 PM | Sat: Closed | Sun: Closed
MUSC Health Florence Rehabilitation Center
★★★★½ (6 reviews)805 Pamplico Hwy 9th Floor, Florence, SC 29505
(843) 674-2665
Website: www.getcare.muschealth.org/locations/sc/florence/musc-health-florence-rehabilitation-centerdep-fac244
Carolinas Hospital System Outpatient Rehabilitation Center
★★★★★ (1 reviews)1925 Hoffmeyer Rd #4011, Florence, SC 29501
(843) 661-4360
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed
MUSC Health Physical Medicine and Rehabilitation
★★★★★ (1 reviews)Medical Pavilion B, 805 Pamplico Hwy Suite 125, Florence, SC 29505
(843) 674-6400
Website: www.getcare.muschealth.org/locations/sc/florence/musc-health-physical-medicine-and-rehabilitationdep-fac304
Hours: Mon: Closed | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–12 PM | Sat: Closed | Sun: Closed
McLeod Work Recovery Center
★★★★★ (1 reviews)2439 Willwood Dr, Florence, SC 29501
(843) 777-2196
Website: www.mcleodhealth.org/services/occupational-health/new-occupational-health-overview
Midlands
★★★★★ (1 reviews)300 Rainbow Dr #4, Florence, SC 29501
McLeod Pediatric Rehabilitation
★★★☆☆ (1 reviews)2439 Willwood Dr, Florence, SC 29501
(843) 777-4075
Website: www.mcleodhealth.org/services/care/childrens-hospital/pediatric-rehabilitation
McLeod Rehabilitation Services
2439 Willwood Dr, Florence, SC 29501
(843) 777-2196
Website: www.mcleodhealth.org/services/care/rehabilitation-overview
Lowe's Rehabilitation Services
507 W Cheves St, Florence, SC 29501
(843) 669-1188
Website: www.lowesrehab.com
About Outpatient Rehab Centers in Florence, SC
Finding the right support for substance use recovery is a deeply personal journey, and for many in Florence, South Carolina, outpatient rehab offers a flexible path forward. As a hub for the Pee Dee region, Florence is a community of hardworking individuals—from healthcare professionals at the local medical centers to small business owners and families. The demands of daily life, including work, childcare, and other responsibilities, can make stepping away for a residential program feel impossible. Outpatient care allows you to attend therapy and counseling sessions while maintaining your job and family commitments, providing a vital bridge between intensive treatment and real-world obligations.
Addiction affects people from all walks of life in Florence, and seeking help is a sign of strength, not failure. Outpatient programs are designed to meet you where you are, offering structured support without requiring a live-in stay. Whether you are looking for a first step after a recent setback or a way to maintain long-term recovery, these centers provide the professional guidance and community connection needed to heal. You deserve a recovery plan that fits your life, and the resources are here to help you build a healthier future, one day at a time.
Frequently Asked Questions
How many outpatient rehab centers are in Florence?
Our directory lists 33 outpatient rehab facilities in Florence, SC.
What is the difference between inpatient and outpatient rehab?
Inpatient rehab requires living at the facility for the duration of treatment. Outpatient rehab allows you to live at home and attend treatment sessions during the day. The right choice depends on the severity of addiction and individual circumstances.
How often do I need to attend outpatient rehab?
Frequency varies by program type. Standard outpatient may be 1-2 sessions per week. Intensive outpatient (IOP) typically requires 3-5 sessions per week for several hours each. Your treatment team will recommend an appropriate schedule.
BeforeRehab.com is an informational directory only. We are not a treatment provider, referral service, or crisis hotline. The information provided does not constitute medical advice. Always verify a facility's credentials, licensing, and insurance acceptance directly. If you or someone you know is in crisis, please call 988 (Suicide & Crisis Lifeline) or SAMHSA's National Helpline at 1-800-662-4357.
Listings are displayed in no particular order. No facility has paid for placement in this directory.
This is not a referral service. We do not endorse or recommend any facility listed.
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