24 Drug Rehab Centers in Greenville, SC

Browse verified drug rehab centers in Greenville, South Carolina. Compare providers and find contact information.

Recovery Centers of America at Greenville

★★★★½ (221 reviews)
47 Fisherman Ln, Greenville, SC 29615
(855) 390-6568
Website: recoverycentersofamerica.com/locations/greenville
Hours: Mon-Sun: Open 24 hours

Encompass Health Rehabilitation Hospital of Greenville

★★★★½ (151 reviews)
3372 Laurens Rd, Greenville, SC 29607
(864) 537-4600
Website: www.encompasshealth.com/locations/greenville-rehab
Hours: Mon-Sun: Open 24 hours

Solutions Recovery Center, Inc

★★★★☆ (166 reviews)
520 Lowndes Hill Rd, Greenville, SC 29607
(864) 567-7010
Website: www.solutionsrecoverycenter.com
Hours: Mon: 8 AM–6 PM | Tue: 8 AM–6 PM | Wed: 8 AM–6 PM | Thu: 8 AM–6 PM | Fri: 8 AM–6 PM | Sat: Closed | Sun: Closed

The Turning Point of South Carolina

★★★★☆ (122 reviews)
24 Bruce Rd, Greenville, SC 29605
(864) 299-0090
Website: www.turningpointofsc.org
Hours: Mon-Sun: Open 24 hours

Phoenix Center

★★★☆☆ (101 reviews)
1400 Cleveland St, Greenville, SC 29607
(864) 467-3790
Website: www.phoenixcenter.org
Hours: Mon: 8:30 AM–5 PM | Tue: 8:30 AM–5 PM | Wed: 8:30 AM–5 PM | Thu: 8:30 AM–5 PM | Fri: 8:30 AM–3 PM | Sat: Closed | Sun: Closed

Crossroads Treatment Center of Greenville, SC

★★★★☆ (51 reviews)
157 Brozzini Ct Suite A, Greenville, SC 29615
(877) 848-9810
Website: www.crossroadstreatmentcenters.com/center/crossroads-of-greenville-sc
Hours: Mon: 5–11 AM | Tue: 5–11 AM | Wed: 5–11 AM | Thu: 5–11 AM | Fri: 5–11 AM | Sat: Closed | Sun: Closed

FAVOR Upstate - Greenville Center

★★★★★ (35 reviews)
355 Woodruff Rd #303, Greenville, SC 29607
(864) 385-7757
Website: favorupstate.org
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Greenville Metro Treatment Center

★★★☆☆ (46 reviews)
602 Airport Rd C, Greenville, SC 29607
(864) 234-7952
Website: www.newseason.com/clinics/greenville-metro-treatment-center
Hours: Mon: 5 AM–1:30 PM | Tue: 5 AM–1:30 PM | Wed: 5 AM–1:30 PM | Thu: 5 AM–1:30 PM | Fri: 5 AM–1:30 PM | Sat: Closed | Sun: Closed

Miracle Hill Overcomers Center

★★★★★ (24 reviews)
1916 N Pleasantburg Dr #4036, Greenville, SC 29609
(864) 631-0088
Website: miraclehill.org/how-we-help/addiction-recovery/overcomers-program
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Vertical Treatment Centers

★★★★☆ (27 reviews)
142 Milestone Way, Greenville, SC 29615
(864) 991-8884
Website: www.verticaltreatmentcenters.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–1 PM | Sat: Closed | Sun: Closed

Alano Club of the Piedmont

★★★★★ (21 reviews)
111 Catalina Dr, Greenville, SC 29609
(864) 268-2240
Hours: Mon: 8 AM–7 PM | Tue: 8 AM–7 PM | Wed: 8 AM–7 PM | Thu: 8 AM–7 PM | Fri: 8 AM–7 PM | Sat: Closed | Sun: Closed

Cypress Center

★★★★½ (22 reviews)
103 S Venture Dr, Greenville, SC 29615
(864) 419-4424
Website: www.cypresscenter.net
Hours: Mon: 9 AM–3 PM | Tue: 9 AM–3 PM | Wed: 9 AM–3 PM | Thu: 9 AM–3 PM | Fri: 12–2 PM | Sat: 9:30 AM–12 PM | Sun: Closed

Greenville Transitions Recovery Center, LLC

★★★★½ (17 reviews)
25 Sweetbriar Rd Suite A-4, Greenville, SC 29615
(864) 528-3370
Website: www.greenvilletransitionsrecoverycenter.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–5 PM | Sat: Closed | Sun: Closed

Miracle Hill Renewal Center

★★★★☆ (16 reviews)
19 Graves Dr, Greenville, SC 29609
(864) 242-2166
Website: miraclehill.org/how-we-help/addiction-recovery/miracle-hill-renewal-program
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Life Line Services - Substance Abuse Treatment

★★★★½ (10 reviews)
16 Mills Ave #8, Greenville, SC 29605
(864) 775-5509
Website: lifelinesvcs.com
Hours: Mon: Closed | Tue: 6 AM–2 PM | Wed: 6 AM–2 PM | Thu: 6 AM–2 PM | Fri: 8 AM–2 PM | Sat: Closed | Sun: Closed

Serenity Village

★★★★☆ (9 reviews)
6 Dunean St, Greenville, SC 29611
(864) 467-3881
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

Greenville Suboxone Clinic

★★★½☆ (5 reviews)
81 Pointe Cir Suite A, Greenville, SC 29615
(864) 499-8360
Website: www.greenvillesuboxoneclinic.com
Hours: Mon: 9 AM–5 PM | Tue: 9 AM–5 PM | Wed: 9 AM–5 PM | Thu: 9 AM–5 PM | Fri: 9 AM–1 PM | Sat: Closed | Sun: Closed

Greenville Recovery Center

★★★★★ (3 reviews)
24 Park Woodruff Dr Suite 100A, Greenville, SC 29607
(864) 215-4500
Website: recoverycentercarolinas.com/greenville
Hours: Mon-Sun: Open 24 hours

Safe Haven Recovery

★★★★★ (2 reviews)
211 Century Dr, Greenville, SC 29607

Imperial Rehab Center Greenville, SC

★★★★★ (1 reviews)
6619 White Horse Rd, Greenville, SC 29611
(864) 519-8328
Hours: Mon-Sun: Open 24 hours

Upstate Intergroup Office

★★★★★ (1 reviews)
1302 Rutherford Rd Side Entrance (Orange Awning, Greenville, SC 29609
(864) 233-6446
Website: www.upstateintergroup.org
Hours: Mon: 10 AM–2 PM | Tue: 10 AM–2 PM | Wed: 10 AM–3 PM | Thu: 10 AM–3 PM | Fri: 10 AM–2 PM | Sat: Closed | Sun: Closed

Prisma Health Recovery Clinic–Greenville

876 W Faris Rd, Greenville, SC 29605
(864) 455-5994
Website: prismahealth.org/locations/practices/recovery-clinic-greenville
Hours: Mon: Closed | Tue: 8 AM–4 PM | Wed: 8 AM–4 PM | Thu: 8 AM–4 PM | Fri: 8 AM–12 PM | Sat: 8 AM–4 PM | Sun: 8 AM–4 PM

Hope for Families

136 Milestone Way, Greenville, SC 29615
(864) 906-2395
Website: www.familyrecoveryacademy.online

Greenville County Commission

1400 Cleveland St, Greenville, SC 29607
(864) 467-3076
Website: www.greenvillecounty.org/Council/boardscomm.aspx
Hours: Mon: 8 AM–5 PM | Tue: 8 AM–5 PM | Wed: 8 AM–5 PM | Thu: 8 AM–5 PM | Fri: 8 AM–5 PM | Sat: Closed | Sun: Closed

About Drug Rehab Centers in Greenville, SC

Finding the right support for substance use begins with acknowledging the need for help, and Greenville offers a growing network of care. Nestled in the foothills of the Blue Ridge Mountains, this vibrant city is known for its strong sense of community and rapid growth. However, like many expanding areas, Greenville also faces rising rates of opioid and alcohol misuse, creating a real need for accessible, compassionate treatment options.

Addiction does not discriminate—it affects professionals, parents, students, and retirees across Greenville’s diverse neighborhoods. Whether you are struggling with prescription medication, alcohol, or other substances, seeking help is a courageous step toward reclaiming your life. Local rehab centers are designed to meet you where you are, offering medical detox, therapy, and long-term recovery planning.

BeforeRehab.com helps you navigate these local options with clarity and hope. By exploring the directory, you can find facilities that align with your personal needs, schedule, and insurance. Recovery is possible, and you don’t have to face it alone.

Frequently Asked Questions

How many drug rehab centers are listed in Greenville, South Carolina?

Our directory currently lists 24 drug rehab facilities in the Greenville, SC area. This number is based on publicly available data and may change over time.

How do I choose a drug rehab center in Greenville?

Consider the types of substances they treat, treatment approaches offered, staff qualifications, insurance acceptance, program length, and aftercare support. Always verify licensing with your state authority.

Does BeforeRehab.com recommend specific facilities?

No. We are an informational directory only. We do not endorse, recommend, or rank any facility. Listings are compiled from publicly available data.

How do I verify a rehab center's license in South Carolina?

Contact your state licensing authority or visit SAMHSA's treatment locator at findtreatment.gov to verify a facility's credentials and license status.

BeforeRehab.com is an informational directory only. We are not a treatment provider, referral service, or crisis hotline. The information provided does not constitute medical advice. Always verify a facility's credentials, licensing, and insurance acceptance directly. If you or someone you know is in crisis, please call 988 (Suicide & Crisis Lifeline) or SAMHSA's National Helpline at 1-800-662-4357.

Listings are displayed in no particular order. No facility has paid for placement in this directory.

This is not a referral service. We do not endorse or recommend any facility listed.

Business owners: to update or remove a listing, email [email protected].

Verify credentials with your State Licensing Authority.

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Important: This website does not provide referrals to any treatment facility. BeforeRehab.com does not receive compensation, kickbacks, or fees of any kind from any treatment center, sober living home, or recovery service listed on this site. No facility has paid for placement, priority positioning, or endorsement. All listings are derived from publicly available data and appear in no particular order. If you need immediate help, call the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).